These traditional Chinese medicine prescriptions are effective in treating COVID-19, and the ＂three drugs and three parties＂ write the anti-epidemic plan of traditional Chinese medicine
Traditional Chinese medicines has played a very good role in controlling and treating the COVID-19 epidemic. After screening and research, Jinhua Qinggan Granule, Lianhua Qingwen Capsule/Granule, Xuebijing Injection, Qingfei Paidu Decoction, Huashi Baidu Formula and Xuanfei Baidu Formula are proved to be effective.
Source: Xinhua News Agency
What are the specific effects of these prescriptions? What crowd is it suitable for? Let’s introduce them to you one by one.
Jinhua qinggan granules
Jinhua Qinggan Granule
Jinhua Qinggan Granule, a Chinese patent medicine developed during the pandemic of influenza A (H1N1) in 2009, is composed of 12 kinds of medicines, including honeysuckle, mint, licorice, etc. Its main functions are dispersing wind, dispersing lung, clearing away heat and toxic materials,Has definite curative effect in treating mild and common patients.It can shorten the time of fever reduction, increase the normalization rate of lymphocytes and leukocytes, and obviously reduce the rate of severe conversion..
Jinhua Qinggan Granule was developed during the 2009 H1N1 influenza pandemic. It consists of 12 herbal components including honeysuckle, mint and licorice and can clear heat and detoxify lungs.
It has a curative effect in treating mild and moderate patientsand can also improve the recovery rate of lymphocyte and white blood cells as well as reduce the rate of patients turning more severe.
China Daily reporter, Department of Traditional Chinese Medicine, Wuhan Sixth Hospital, Wang Jingshe
Zhang Boli, a member of the expert group of the Central Steering Group, an academician of China Academy of Engineering and president of Tianjin University of Traditional Chinese Medicine, said that the two projects that have been carried out have found that Jinhua has a good effect of clearing the senses. At the beginning of February, after the treatment of 102 patients with mild and common COVID-19 in Wuhan, it was found that the weight transfer rate of patients decreased significantly, only 11.8%. The patient’s fever reduction time is only 1.5 days.
In early February, 102 mild patients in Wuhan took Jinhua Qinggan Granule in their treatment. Only 11.8 percent worsened and it took only one and a half days for patients to reduce fever.
A controlled study of 80 cases conducted by Professor Xuexiu Li from the Fourth Medical Center of the General Hospital of the People’s Liberation Army in Beijing You ‘an Hospital also found that the time for nucleic acid to turn negative was two and a half days earlier than that of the control group, and the average time for lung inflammation to improve was 8 days, while that of the control group was 10.3 days.
A comparative experiment showed that patients who took Jinhua Qinggan Granule tested negative for coronavirus two and a half days earlier than a group that did not take the granule. The group treated with the granule also took eight days to show improvement, while the other group took 10.3 days.
Lianhua Qingwen Capsule/Granule
Lianhua Qingwen Capsule/Granule
Lianhua Qingwen capsule/granule is composed of 13 kinds of medicines, which is a commonly used Chinese patent medicine for treating colds and flu. Its main functions are clearing away fever and toxic materials, dispersing lung qi and clearing heat.The treatment of mild and common patients shows curative effect, especially the fever, cough and fatigue disappear quickly, which can reduce the occurrence of mild and common patients and promote the nucleic acid to turn negative..
Lianhua Qingwen medicine is a very common traditional Chinese medicine used for the treatment of cold and flu. Composed of 13 herbal components, it has shown curative effects on mild and common patients, especially in relieving fever, cough and fatigue. It can reduce the occurrence of deterioration and help patients test negative.
Xuebijing injection
Xuebijing Injection
Xuebijing injection, a Chinese patent medicine developed and marketed during SARS in 2003, is composed of five Chinese herbal extracts. Its main function is to remove blood stasis and detoxify, and it is used to treat sepsis.
This injection was developed and marketed during the severe acute respiratory syndrome (SARS) epidemic in 2003. It consists of five herbal extracts and its main function is to detoxify and remove blood stasis. It is usually used to treat sepsis.
In the treatment of severe and critical patients, it is suitable for systemic inflammatory response syndrome induced by infection, and can also be used to treat multiple organs and organ dysfunction.Preliminary clinical research shows that the combined use of western medicine can improve the rate of cure and discharge, and reduce the conversion from severe to critical illness. The basic research has preliminarily found that it has certain antiviral effect in vitro and can significantly inhibit the inflammatory factors induced by novel coronavirus infection.
It is effective in suppressing systemic inflammatory response syndrome induced by infection in the treatment of severe and critically ill patients as well as repairing impaired organ function.
Initial clinical studies have shown that the injection, combined with Western medicine, can increase the rate of hospital discharge and reduce the rate of deterioration. Basic research has also found that it has a certain antiviral effect in vitro that can significantly inhibit inflammatory factors induced by novel coronavirus infection.
In addition to treating inflammatory reaction and preventing cytokine storm, Xuebijing also has antithrombotic function, because this time COVID-19 will also lead to excessive coagulation function and thrombosis everywhere in the body, which will cause organ embolism and damage tissues, and Xuebijing can protect endothelial cells well, prevent excessive coagulation in the body and prevent the formation of microthrombosis.
The novel coronavirus also tends to cause excessive clotting in the body that leads to organ embolism and damages tissues, and Xuebijing can help prevent excessive coagulation and the formation of thrombus.
Previously, led by Professor Bai Chunxue from Zhongshan Hospital of Fudan University, a randomized controlled trial of Xuebijing was conducted in 33 hospitals. According to the data analysis of 710 cases,Xuebijing combined with routine treatment can reduce the 28-day mortality of patients with severe pneumonia by 8.8% and shorten the hospitalization time in ICU by 4 days..
A comparative experiment of 710 cases jointly conducted by over 30 hospitals showed that the injection combined with regular treatment can reduce the m ortality rate of severe patients by 8.8 percent and shorten intensive care unit hospitalization by 4 days.
The Xuebijing project, led by members of the expert group of the Central Steering Group, Qiu Haibo, vice president of Zhongda Hospital affiliated to Southeast University, Academician Zhong Nanshan, and Director Song Yuanling of Zhongshan Hospital, has been applied to the severe and critically ill patients in COVID-19 since the end of January. At present, 156 patients in 32 hospitals have used Xuebijing. Good results have been achieved.
Another project saw Xuebijing Injection applied clinically to severe and critical patients from the end of January, with 156 patients in 32 hospitals treated. They all achieved very good improvements.
According to Qiu Haibo, the clinical safety study of Xuebijing after marketing shows that the adverse reaction rate is about 0.3%, which is a very safe figure, and it will not be rejected with other antibiotics and other treatments.
Research on the clinical safety of Xuebijing also showed that the adverse reaction rate was about 0.3 percent, which is a very safe figure, and it will not react adversely with other antibiotics or treatment.
Qingfei Paidu Decoction
Lung Cleansing and Detoxifying Decoction
Qingfei Paidu Decoction is the first choice of Chinese medicine in the novel coronavirus Diagnosis and Treatment Plan (Trial Seventh Edition) published in early March. Since February 6th, National Health Commission and state administration of traditional chinese medicine have jointly issued a document recommending Qingfei Paidu Decoction to the whole country.
Qingfei Paidu Decoction comes from several classic recipes in Zhang Zhongjing’s Treatise on Exogenous Febrile Diseases. There are 21 herbal components in the whole recipe, and its main functions are dispersing lung qi, eliminating pathogenic factors, clearing heat and eliminating dampness, and invigorating spleen and resolving fluid.Mainly in improving symptoms such as fever, cough, fatigue, etc., it takes effect quickly and obviously, and can effectively promote the improvement of lung imaging in severe patients..
LungCleansingandDetoxifying Decoctionis derived from several classic recipes in a traditional Chinese medicine work known in English as Treatise on Col d Damage Diseases, which was written by Zhang Zhongjing sometime before 220 AD. It has 21 herbal components and is mainly effective in improving symptoms of fever, cough and fatigue as well as lung condition, as shown by CT scans, in severe patients.
Clean: clean, clean
Detoxify: detoxify, remove toxins
Decoction: boiling agent
Basic research shows that this prescription can regulate many cell signal pathway)— — Information is transmitted between cells to achieve the purpose of inhibiting virus replication, so as to avoid or alleviate the inflammatory storm & mdash; — Cytokines are overreacted by virus infection and other incentives, regardless of friends or enemies, causing harm to themselves. It focuses on the lung and protects multiple organs at the same time, which can be used as a general prescription for the treatment of light, ordinary, heavy and critical patients.
Studies have proved the decoction can regulate multiple cell signaling pathways – cells communicating with each other by receiving and processing chemical signals in response to environmental changes – to inhibit virus replication and avoid or mitigate cytokine storms, which are an overreaction of cells that damages the immune system.
The decoction targets lungs and can also protect other organs. It can be used as a general recipe for treating mild, moderate, severe and critical patients.
According to Tong Xiaolin, an expert of the Central Steering Group, the leader of the state administration of traditional chinese medicine Expert Group, the chief researcher of the Chinese Academy of Traditional Chinese Medicine and an academician of the China Academy of Sciences, so far, 1,261 COVID-19 patients in 10 provinces have been cured, 29 cases have disappeared and 71 cases have improved after taking the "Qingfei Paidu Decoction". Among them, 28 cases have been discharged from the hospital after taking 40 cases of severe patients; 12 cases were treated in hospital, 10 cases got better symptoms, "from severe to mild", and none of them changed from mild to severe or critical.
Tong Xiaolin, chief researcher of the Chinese Academy of Chinese Medical Sciences and also an academician of the Chinese Academy of Sciences, said 1, 261 novel coronavirus patients in 10 provinces took the decoction, with 1,102 recovering, symptoms no longer appearing in 29, a further 71 showing improvement and no cases deteriorating.
There were also 40 severe patients. After taking the medicine, 28 were discharged from hospital, and the condition of 10 improved, with their symptoms changing from severe to mild.
Huashi Baidu recipe
Huashibaidu Formula
The prescription of eliminating dampness and removing toxin is a core prescription, which is summarized and condensed by the National Medical Team of Traditional Chinese Medicine (Chinese Academy of Traditional Chinese Medicine) on the basis of the prescription recommended by the early national diagnosis and treatment plan and combined with the clinical practice in Jinyintan Hospital. There are 14 kinds of traditional Chinese medicines in the whole prescription.
Huashibaidu Formula is a core recipe developed by the national traditional Chinese medicine team from the China Academy of Chinese Medical Sciences. Co mposed of 14 herbal components, the formula is based on the recommendations of the early national diagnosis and treatment plan as well as the experiences from clinical practice at Wuhan Jinyintan Hospital.
China Daily reporter Wang Jingshe
Its main functions are detoxicating, eliminating dampness, clearing away heat and relieving asthma, and it is suitable for the treatment of mild, common and severe patients.This prescription can play a multi-link comprehensive treatment role in COVID-19, which can obviously shorten the time of negative nucleic acid conversion and the average hospitalization days, obviously improve the clinical symptoms, and promote the physical and chemical examination and the improvement of lung CT. Through the evaluation of novel coronavirus mouse model, it is found that this prescription can reduce the viral load of lung tissue by 30%.
Its main efficacy is to detoxify, remove dampness and heat from the body and relieve cough to achieve an inner body balance. It can be used to treat light, moderate and severe patients.
This prescription has a comprehensive treatment effect in different stages of novel coronavirus pneumonia and can significantly shorten the length of h ospital stay and improve clinical symptoms and lung condition as shown by CT scans and other examinations. Studies on guinea pigs found the formula can reduce lung viral load by 30 percent.
Xuanfei Baidu Granule
Xuanfeibaidu Granule
Xuanfei Baidu prescription is also derived from several classic famous prescriptions, and there are 13 kinds of Chinese medicines in the whole prescription.
Xuanfeibaidu Granule, with 13 herbal components, originates from several classic traditional recipes.
Its main functions are dispersing lung qi, eliminating dampness, clearing away heat, expelling pathogenic factors, purging lung qi and detoxicating, and it is suitable for the treatment of mild and common patients.Relevant research shows that this prescription can shorten the time of disappearance of clinical symptoms, the time of normalization of body temperature, and the average length of stay of COVID-19 patients, and to some extent, it can block the conversion from mild to severe.
It can detoxify the lungs and clear dampness and heat and is used for treating light and moderate patients. Research has shown the prescription can sho rten the time it takes for clinical symptoms to vanish and temperature return to normal and can effectively prevent light and moderate patients from deteriorating.
China Daily reporter Wang Jingshe
State administration of traditional chinese medicine data show that as of 0: 00 on March 15th,The proportion of Chinese medicine participating in treatment in Hubei Province is 91.64%, that in Wuhan is 89.10%, and that in China is 92.41%.The participation of Chinese medicine has always been a very important part in the national diagnosis and treatment plan, and it has attracted great attention from the beginning of the epidemic. Not only three expert groups of Chinese medicine academicians have been sent to Wuhan to carry out their work, but also five batches of national Chinese medicine medical teams have been sent to help Wuhan.
A large number of clinical data and observations show that,Traditional Chinese medicine has obvious effects in early prevention, preventing the transition from mild illness to severe critical illness and recovery period after cure, and the combination of traditional Chinese medicine and western medicine has greatly reduced the severe and fatal rates.Experts have repeatedly stressed that Chinese medicine is a good way to treat COVID-19 when there is no effective vaccine and specific medicine, which provides another way to fight the epidemic.
Yang Yi, the chief physician of Hubei Provincial Hospital of Traditional Chinese Medicine, said in an interview with China Daily that western medicine often pursues targeted drugs, and when there is inflammation, it will diminish inflammation, and when there is virus, it will kill the virus or produce antiviral antibodies, while Chinese medicine uses a different system, which pursues the balance of yin and yang inside the body, and fights against external infections by adjusting the overall immunity.
Liu Qingquan, an expert of the Central Steering Group, deputy head of the National Expert Group on Medical Treatment of Traditional Chinese Medicine and president of Beijing Hospital of Traditional Chinese Medicine, once said:"It’s like eating. Whether it is steamed bread or bread, it is good to make people eat well. There is no difference between steamed bread and bread itself. "
Reporter: Zhang Yangfei, Wu Yong
Source: China Daily.