Haikou plans to impose a fine on Lexus 4S store for "suspected price increase" and put it on the list of serious violations of law and dishonesty.

Haikou, China Broadcasting Network, March 20 th Recently, Haikou Zhongsheng Lexus Automobile Sales & Service Co., Ltd. was suspected of increasing the price outside the price, which caused widespread concern after being exposed by the media. On the morning of March 20th, the reporter learned from Haikou Municipal Market Supervision Administration that the market supervision department planned to impose an administrative penalty of 450,000 yuan for the company’s price fraud that refused to fulfill its price commitment without justifiable reasons, and put it on the list of serious violations of law and dishonesty.

Haikou Zhongsheng Lexus 4S Store (photo by Yang Guangwang reporter Cai Wenjuan)

In January this year, Mr. Wang, a citizen, ordered a car in Haikou Zhongsheng Lexus 4S store (affiliated to Haikou Zhongsheng Lexus Automobile Sales and Service Co., Ltd.). After signing the contract and paying the deposit, the salesman asked for an additional service fee of 100,000 yuan as a condition for picking up the car. After being rejected by Mr. Wang, the salesperson unilaterally returned the car purchase deposit. After the competent departments of commerce, market supervision and other industries in Haikou intervened in the investigation, on March 14th, the 4S store issued an apology statement and dismissed the customer service manager involved.

Administrative Law Enforcement Detachment of Haikou Municipal Market Supervision Administration (photo by Yang Guangwang reporter Cai Wenjuan)

On March 20th, a notice that Haikou Municipal Market Supervision Administration was included in the list of serious violations of law and dishonesty (hereinafter referred to as the "notice") was circulated on the Internet. After verification by the reporter, it was confirmed as the relevant documents issued by Haikou Municipal Market Supervision Administration.

The "Notice" shows that Haikou Zhongsheng Lexus Automobile Sales & Service Co., Ltd. failed to fulfill its price commitment and put forward an unreasonable request to raise the price by 100,000 yuan beyond the agreed price. After the consumer Wang refused, he unilaterally returned the deposit. Haikou Zhongsheng Lexus Automobile Sales & Service Co., Ltd. is suspected of violating Item 4 of Article 14 of the Price Law of People’s Republic of China (PRC) and Item 3 of Article 2 and Item 5 of Article 19 of the Provisions on Clearly Marking Prices and Prohibiting Price Fraud, which constitutes a price fraud that refuses to fulfill the price commitment without justifiable reasons. According to Article 23 of the Provisions on Clearly Marking Prices and Prohibiting Price Fraud and Article 7 of the Provisions on Administrative Penalties for Price Violations, Haikou Municipal Market Supervision Administration intends to impose an administrative penalty of RMB 450,000 on Haikou Zhongsheng Lexus Automobile Sales & Service Co., Ltd..

According to Article 2, Paragraph 2, Item 1 and Article 9, Item 6 of the Measures for the Administration of Market Supervision and Management of Serious Violations of Law and Trustworthiness, it is now decided to include Haikou Zhongsheng Lexus Automobile Sales & Service Co., Ltd. in the list of serious violations of law and trustworthiness, publicize it to the public through the national enterprise credit information publicity system, and implement corresponding management measures. The inclusion period is three years from the date of inclusion.

On the morning of the same day, Yuan Renxiang, a case handler of the Administrative Law Enforcement Detachment of Haikou Municipal Market Supervision Administration, introduced in an interview that after receiving the case clue letter forwarded by Haikou Municipal Bureau of Commerce, Haikou Municipal Market Supervision Administration immediately organized the case handlers to go to the scene to investigate and collect evidence and issue handling opinions. During the period, the case-handling personnel collected complaints related to the 4S shop since 2019, and found no similar situation. At the same time, during the investigation, the case-handling personnel contacted Mr. Wang many times, but they failed to get in touch, which also caused certain difficulties in the investigation process.

The case-handling personnel were interviewed by reporters (photo by Yang Guangwang reporter Cai Wenjuan)

Yuan Renxiang said that at present, the relevant investigation results have come out, and the Haikou Municipal Market Supervision Administration has also issued a Notice, which was delivered to the person in charge of the enterprise involved on the evening of March 19.

Li Kexiong, the captain of the Fourth Brigade of the Market Supervision Administrative Law Enforcement Detachment of Haikou Municipal Market Supervision Administration, said that the case is still being processed. After the Notice is delivered to the enterprises involved, the enterprises have five working days to appeal. After 5 working days, if there are no other circumstances, the market supervision department will issue a "Penalty Decision" in accordance with relevant procedures.

The relevant person in charge of the office of Haikou Municipal Market Supervision Administration told the reporter that the market supervision department has not strictly defined the behavior of adding value-added service fees to some businesses. "Any fee must be clearly marked and the service content is clear. Sales staff should inform consumers in advance before charging, and consumers have the right to choose to accept or refuse. " The person in charge said.

The person in charge reminded consumers not to trust the verbal promises of the merchants when buying a car, but to sign a car purchase contract, pay attention to whether the terms of the car purchase contract are complete, clearly stipulate the necessary elements of the purchased car, and list the total price, payment method and time limit of the vehicle transaction, delivery method and time limit of the vehicle, as well as the handling of quality disputes and objections and the liability for breach of contract, so as to avoid the difficulty of proof when defending rights and earnestly safeguard their legitimate rights and interests.

(The original title is "Haikou Municipal Market Supervision Bureau intends to impose a fine of 450,000 yuan on Lexus 4S shop for" suspected price increase "and list it in the list of serious violations of law and trust")

China Laboratory | Wang Peng: Engine manufacturing in China is not a technical problem.

Wang Peng, General Manager of Engineering and Technology of GE Aviation Group in China.

Aero-engine manufacturing is the crown in the industrial system, and it is highly sensitive, which is the technology that China has been longing for. In the past, in the general habitual expression, aero-engines were highly related to the western technical blockade of China.

In recent years, China has stepped up the independent research and development of aero-engines, and China’s huge aviation market has also shown strong attraction, and major aviation giants have more careful consideration of their own interests. Under the comprehensive effect of various factors, the manufacturing of China local aero-engines has made great progress. In January, 2016, in an exclusive interview with The Paper, Wang Peng, general manager of engineering technology in China of GE Aviation Group, talked about the so-called "technical blockade".

In fact, in the process of localization of cutting-edge technology of western giants, we should give up prejudice and fully believe in the power of the market. It is believed that based on the principle of mutual benefit, there is no technical blockade that harms others and does not benefit others. On the premise of observing the rules, in fact, everything can be discussed.

GE attaches great importance to training local talents in China.

The Paper:How many people in GE China serve the ARJ21 project?

Wang Peng:As the first engineer of the ARJ21/CF34-10A project team, I arrived in Shanghai in 2003. In the past ten years, in China, our engineering team has done three things. One is related to the engine, including the ARJ21 project and the ship project. The second block is the supply chain support of the whole region, covering Chinese mainland, Taiwan Province and other regions. The third is aviation services. I am mainly doing these three aspects of work now. (ARJ21 is a regional aircraft with independent intellectual property rights developed by China according to international standards. CF34-10A is an engine used by ARJ21 and manufactured by GE Aviation Group. -editor’s note)

There aren’t many of us, only 140 in all. On the ARJ21/CF34-10A project, there are only four of us today. This project has passed the peak stage, and the next step is to support it how to enter the airlines to run. At present, these four people are very important, and two Model Leader will be trained for this model in the future, one is the engineering chief engineer of CF34-10A, and the other is the service chief engineer of CF34 family engine. Although there are only four people in China, they can mobilize global resources to support this project. The reason why such a key chief engineer is transferred to China is to better support China’s aircraft project and airline operation. These two chief teachers are very young, both born in the 1980s.

The PaperChief engineer means to be responsible from design to production?

Wang Peng:The chief engineer is responsible for the whole life cycle of this model. For example, COMAC (China Commercial Aircraft Co., Ltd.) is the chief engineer of engine design for wide-body aircraft, responsible for the progress of the project, the determination and review of technology, fund management, and how to mobilize global resources to implement the development of this project. This chief engineer is in China, but the whole design team may not be in China in the future. There are American teams, Indian teams and Polish teams. This chief engineer should be able to mobilize all resources to serve this project.

The Paper:Since there has been a mature design process and a mature head teacher before, why should we put a new head teacher and set up a new team in China?

Wang Peng:Because ARJ21 and wide-body aircraft are both aircraft models of China, and the customers are in China. In the long run, this position is most suitable in China. It can be seen from this that GE is very open. GEnx-1B/2B is the model chief engineer of the third service in the world in China, and now he is training in the United States. Now I’m talking about the work scope of GE90′ s overall system leader in China, and I’ll decide soon and start recruiting. The model chief engineer of LEAP-1C will also be in China in the future. Most of these people are born in the 1980s. Although they are in China, their functions are actually very extensive. Depending on different types of engines, they can cover Australia and New Zealand in the south and Japan in the north. (GEnx-1B/2B and GE90 are engines produced by GE Aviation Group. LEAP-1C is the only designated foreign engine of China’s first large aircraft C919, which is manufactured by CFM, a joint venture between GE and Safran Group. -editor’s note)

At GE headquarters, it is impossible to get this position organically without 20 years’ working experience, but in China, it can be seen that GE attaches importance to and cultivates China. At present, there are less than 20 commercial engine models operated by GE, and the chief engineer of so many models is Chinese, which is a great decentralization to us. On the other hand, this is what our China team has been striving to prove its strength, build trust and constantly break through man-made obstacles for so many years, driven by market demand.

Strictly abide by the laws of China and the United States in intellectual property rights.

The Paper:Are you worried about intellectual property rights?

Peng WangIntellectual property rights are like this. We must abide by the laws of the United States and China at the same time. Intellectual property sometimes becomes an excuse. Secondly, this is a wall in many Chinese’s heart. Before we start making it, there is a wall there that we can’t cross.

It is normal and understandable that Americans are worried about intellectual property rights in China. In this case, we should protect intellectual property rights better, so that everyone can rest assured and work can be carried out. The same is true of export restrictions. We must strictly abide by the laws of the two countries and cannot make any mistakes in export restrictions. But this does not mean that we can do a lot of things without doing it, within the scope permitted by law. This is my view on intellectual property protection and export restrictions. If you want to do everything, you have a hundred ways to do it. If you don’t want to do something, there are a hundred reasons not to do it.

The Paper:We always feel that intellectual property rights have thorns and cannot be touched.

Wang Peng:You think that you are shorter than others, and you always think that others will bully you. This is a psychological state of inferiority, which makes you unable to get along with others. Let’s face this problem. We have done a lot of work on export restrictions, because as a supply chain support, we can’t limit our work to China. Our goal is the whole Asian region. If I want to do this, I must understand the legal restrictions on the export of related products in the United States, otherwise I may violate the rules, or many people will say that there are export restrictions here and Chinese cannot do it.

Then, let’s talk to lawyers who specialize in export restrictions, look at one legal clause after another, analyze one part by one, and study one factory by one to see what risks there will be. In the end, we got the answer that we can do a lot of things.

Before doing this, many people will use this as an excuse to say that you can’t do this or that, or we have limited ourselves in our hearts. Therefore, when you encounter this kind of problem, there is no way to avoid it, but to solve it face to face. We can talk about these things in the open. Otherwise, either limit yourself to death or violate the rules, which will cause problems.

It is not a manufacturing technical problem that China can’t make an engine.

The PaperWhat is the technology spillover effect of foreign companies?

Peng WangMany parts of GE’s engine are made in China.

The most restrictive export is the hot-end component, that is, the high-pressure turbine. The blades of the high-pressure turbine are not made in China, but the high-pressure turbine disk is made in China. The high-pressure turbine shroud ring, which we studied in the past, can be made in China, but the last one was not brought here because of economic problems, not export restrictions. The combustion chamber can’t be made in China, but the head of the combustion chamber has been made in China, and the engine casing from beginning to end has been made in China. There are many rotors in the engine, and the discs of the rotors are all made in China.

There is a special supplier for bearings. I haven’t investigated carefully whether this supplier is in China. The engine has two shafts, one is the shaft of high-pressure rotor, which we made in China; The shaft of the low-pressure rotor was not made in China because the current technology in China is not good, and we are developing it, but we haven’t developed a very good qualified product, so we didn’t make it in China. There are also engine blades. Our high-pressure turbine blades cannot be made in China, which is the requirement of export restrictions. Other blades were not made in China, not because of export restrictions, but because it was uneconomical to make them in China. Blade of low pressure turbine, our partner has already made it in China.

So, as you can see, what an engine can’t do in China is too limited. You say that the China engine can’t be made is a manufacturing technical problem, which is pure nonsense. This is not a problem. Even if the high-pressure turbine blades are not made in China, the high-pressure turbine drilling technology is developed in China, and many things can be made in Chinese.

We help China suppliers grow rapidly.

The Paper:What is the growth of GE’s downstream suppliers in China?

Peng WangWe cooperate with suppliers. We have helped China suppliers grow very fast in recent years. The first growth is from not being able to do it to being able to do it. It took us a long time, more than ten years, to train China suppliers to be able to do it. Second, if it can be done, it should be more economical and competitive. It is also our team that has done a lot of work to make our suppliers do better.

Then, we don’t just consider the problem from the perspective of processing. From the perspective of industrial chain, the main characteristics of China’s manufacturing industry are that both ends are outside, raw materials are imported, and the market is abroad. Buy raw materials from abroad, do technical processing, and then export. This industrial model is unsafe. Since 2011, I have been promoting the localization of raw materials, not just machining in China, but also producing raw materials in China. It took us four or five years, and now the suppliers in China have almost been trained. Now many forgings are made in China, and some castings have been made in China.

We push further upstream, and the upstream is high-temperature alloy. If these high-temperature alloy factories are cultivated into qualified suppliers of GE, this line will be on the line, from the production of high-temperature alloy to the production of forgings and castings to the mechanical processing production, all in China. When our industrial chain is built, it will be very stable.

The Paper:Is it a big investment?

Wang Peng:Investment is investment, not as big as the outside world thinks. Our funds are very limited, and we rely more on market leverage to solve problems. We have invested a lot in technology, and I have a lot of engineers who just do technology. This is how to develop new parts and new processes.

For example, the latest LEAP engine we are making now has a very difficult part, which is a guide behind our high-pressure compressor, and that is a very, very difficult part to machine. Three or four years ago, our team of engineers from GE Aviation Engineering Department cooperated with a company in the manufacturing laboratory of GE Shanghai R&D Center to process this piece with the latest technology. After the final processing technology was developed, the processing time was shortened by half compared with that of American suppliers at that time. We developed this technology and gave it to our supplier in China for free, so that they can be manufactured. At present, Xi ‘an Aero Engine Co., Ltd. is the main supplier of this part. This is an example of how to use technology to promote the development of manufacturing industry.

Excessive speculation is a risk.

The Paper:GE doesn’t worry about suppliers getting up, but another company will integrate them and compete with you?

Wang Peng:In a market economy, we don’t speculate excessively, and everything is very simple. A lot of things are done, and if you don’t do anything, you are afraid of unnecessary risks, then you can’t do it. To solve the problem, we should put all the problems on the table. What’s the good of you doing this? I guess I’m willing to talk to him if I dare to put it on the table. Excessive speculation is a risk, and many misunderstandings and suspicions can be overcome if they are put on the table.

The Paper:Aren’t there many restrictions on American technology exports to China?

Peng WangI went to many universities to enroll students, and many people told me: What you GE did in China is not the core technology of engines. What can you learn? I said, some people always see what they don’t get, and often don’t cherish what they get. Let’s not talk about those core technologies yet. First, there are many export restrictions, and people will not give them to you. Second, China doesn’t do these businesses at all. Why should I give them to you? Let’s throw this piece away first.

What has been given to you now, how is it going? Is everything that Chinese has got ready? For example, with so many suppliers, we give you drawings and specifications. Can you do it? The answer is often: I can’t do it. I will send many engineers to help him do it. If you can’t do everything I give you, and you still cry and shout all day, this logic is untenable because I can’t develop because of restrictions. That’s the excuse.

There are many private suppliers now.

The Paper: How to train suppliers and what kind of supplier training to choose?

Peng WangAt present, the main suppliers are state-owned enterprises, and the enterprises of AVIC (aviation industry corporation of china) are the main ones. They have a good foundation, as most of our suppliers do now. But we are constantly developing new suppliers, and now more private companies have come in. In the past, there were no people looking for private enterprises. With the development of the national economy, there are many private suppliers, and the proportion is increasing little by little. Although there are very few now, you can see their growth.

As our supplier of forgings, it is private and doing well. You will see more and more private suppliers coming in among these new fields. When I was developing them, I particularly emphasized that you should have raw materials. The aviation industry is very different from other manufacturing industries in processing, that is, there are many special processes. The establishment of independent special process capability will greatly help the development of private enterprises. Special technology needs the accumulation of enterprises for many years. If private enterprises only do a simple technical processing without special technology, it is difficult to survive. Without the resources of these special technology suppliers in the market, private enterprises cannot develop.

In the development of our supply chain, this is a very important step, raw materials are particularly important, independent special process capacity building is also very important, and the entry of private economy is also very important. So we are a complete supply chain.

The Paper: Is your technology provided to suppliers, paid or free?

Peng Wang: We are basically free. The motivation for us to do this comes from the parts we made in this area, which are more competitive in price and cheaper than those purchased elsewhere. This reduction in procurement cost is enough for us to support these engineers. Relying solely on morality to restrain people is unsustainable and must be mutually beneficial.

We can do a lot of things in Chinese, depending on whether we have the opportunity to do it.

The Paper:What services have you provided for C919?

Wang Peng:C919 engine system integration, flight test and evidence collection are all done by CFM. GE has two parts in the middle of C919, one is the propulsion system, which we made; The other is avionics. We have a joint venture with AVIC. The propulsion system is mainly made by CFM in the field, from system-level design to flight test and evidence collection. We have done more on C919 than on ARJ21. The structural design of the engine nacelle was done by our team in China. The design of engine peripheral pipeline is also designed by our team in China. (CFM is a joint venture between GE and Safran Group of France, and is the world’s leading supplier of civil aircraft engines. -editor’s note)

When I took over this team in 2008, there were 22 people, few people and limited ability. I thought from that moment, how can we develop further. In 2010, a strategic conference on the division of labor in various regions of the world will be held in the United States. There are three themes, one is manufacturing, the other is engine design, and the other is aircraft system. We have been manufacturing for many years, and I was only invited to the manufacturing sub-meeting. I think if we don’t fight for it, how can we have a chance to enter the other two fields? I took two people, one to attend the engine design meeting, one to attend the manufacturing meeting, and I went to the aircraft system meeting myself.

At the meeting, everyone introduced their abilities. At that time, an Indian team talked about how powerful they were. At that time, the Indian team had 400 to 500 people, Poland had more than 300 people, and Mexico had 600 to 700 people. We couldn’t compare with them at all. They all talked about how powerful they were, and when they all finished, I said we should talk about it. In the field of aircraft systems, our team’s capability is zero. I clicked a point on the blackboard, but considering the capability of China R&D Center, we are not zero, so I drew a circle on it. If we consider the ability of suppliers, we will be even bigger. Of all the countries where global engineering teams are located, only China can make airplanes and rockets. Our GE China team has zero ability now because we have not been given the opportunity to do it before. If I am given the opportunity, I will definitely build up my ability.

In this way, from then on, we built the system structure design team from scratch, and the head of the C919 nacelle fan cover was in China. I have always wanted to say that there are many things we can do in Chinese, depending on whether we have the opportunity to do it. I graduated for more than 20 years now, and my work is simply summed up, that is, I am doing the process from zero to one.

The Paper:What is the confidence that China can do many things?

Peng WangThe C919 project is here, and the market itself has such a demand. If this project is a Boeing project and we do it in China, this reason is not so good. Of course, if we are the best team in this field, I think we can also do Boeing projects. Second, China has people and is rich in engineers. China graduates 7 million college students a year. No country in Europe has these people. I have been to the Czech Republic. They graduate 3600 college students a year. How can they compare with us? There is no way to compare resources. Moreover, engineers in China are very hard-working. At night, there are many engineers working overtime on our floor. I often advise them to leave early, but no one wants to leave. Also, you have to follow a very standardized process, plus resources, a lot of things can be made.

One COVID-19 vaccine hits two people, is it wrong? Guangdong CDC responded!

National Covid-19 vaccine

The vaccination work is being carried out in an orderly manner.

Recently,

When some citizens went to vaccinate, they found that,

A bottle of vaccine can be used by two people,

Is it the wrong number?

Is this standard operation?

On May 11th, Guangdong CDC responded: Don’t worry! This is a two-person packaged COVID-19 vaccine that has just come on the market, and one bottle can be used by two people.

△ Xinhua News Agency reporter Chen Zeguo photo

What is a two-person package?

COVID-19 vaccine?

Two-person package means that one vaccine can inoculate two people, and each bottle is 1.0 ml (dosage for two people), and the dosage for each person is 0.5ml. The vaccine packaged for 2 people is exactly the same as the vaccine packaged for 1 person, except that the packaging color and filling dose are different, which does not affect the individual vaccination effect.

In fact, many vaccines are packaged in multiple doses. For example, the BCG vaccine vaccinated in obstetrics at birth is packaged in five doses, the live attenuated polio vaccine (drops) in children’s immunization program is packaged in ten doses, the group A meningococcal vaccine vaccinated at the age of six months is packaged in five doses, and the diphtheria vaccine vaccinated at the age of six is packaged in four doses.

Therefore, whether it is the vaccination effect of the vaccine or the doctor’s operation technology, everyone does not need to worry, and can be vaccinated with confidence.

△ Source: Xinhua News Agency

2-person packaged vaccine

What are the advantages?

Vaccine supply guarantee is the key factor to actively and steadily promote vaccination in Covid-19. At present, the production capacity of Covid-19 vaccine in China is greatly influenced by filling and packaging. With the approval of relevant state departments, COVID-19 vaccine manufacturers will successively produce a single COVID-19 vaccine packaged for two people.

Two-person packaging can improve the production efficiency and supply of vaccines, so that more people can get vaccinated as soon as possible, especially suitable for large-scale vaccination at present.

2-person packaged vaccine

Do you want two shots, too?

Like the vaccination procedure for a single dose, the vaccine packaged for two people needs to be vaccinated twice in the whole process, and the interval between the two doses is suggested to be greater than or equal to 3 weeks (21 days), and the second dose should be completed as soon as possible within 8 weeks (56 days).

The first shot was a single shot,

Can the second injection be used for two people?

The Guangdong Provincial Center for Disease Control and Prevention said that it can be vaccinated. At present, all Covid-19 vaccines used in Guangdong are inactivated vaccines. If the first shot is inactivated vaccine, no matter whether the manufacturer is Beijing Kexing or China Bio, two doses of inactivated vaccine can be selected for the second shot.

△ Source: Xinhua News Agency

At present,

The national cumulative report of vaccination against Covid-19 vaccine.

It has exceeded 300 million doses!

However, on May 8th, Zhong Nanshan, an academician of China Academy of Engineering, said by video that China, as a populous country, has withstood the first stage of the epidemic since the COVID-19 epidemic occurred more than a year ago, but it can’t be ignored. "Now the global epidemic situation is still very grim, and the vaccination rate of China vaccine is still not high, which is far from universal immunization, so we still need to attach great importance to it and guard against the risk of importing the epidemic."

At present, the global epidemic situation in COVID-19 has not ended, and some countries have even lost control of the epidemic situation. We are always exposed to the risk of the epidemic situation and are always affected by imported cases. Therefore, timely vaccination is the safest, most efficient and most economical way to realize group immunity.

Five Domestic COVID-19 Vaccines

Approved conditional listing or emergency use

Beijing Bio-COVID-19 Vaccine, a national medicine, stands out from the encirclement and is the first to be certified by the World Organization. It is also the only inactivated vaccine among the six approved vaccines.

At the beginning of the epidemic, China laid out five technical routes for vaccine research and development: inactivated vaccine, adenovirus vector vaccine, gene recombination vaccines, attenuated influenza virus vector vaccine and nucleic acid vaccine. At present, three Covid-19 vaccines produced by five manufacturers have been approved for conditional marketing or emergency use.

Three kinds of inactivated vaccines

It was produced by Sinopharm Group China Bio-Beijing Institute of Biological Products Co., Ltd. (Beijing Institute), Wuhan Institute of Biological Products Co., Ltd. (Wuhan Institute) and Beijing Kexing Zhongwei Biotechnology Co., Ltd. (Kexing Zhongwei) respectively. The main principle is to use African green monkey kidney (Vero) cells to culture and amplify the virus, inactivate the virus by β-propiolactone, retain antigen components to induce immune response, and add aluminum hydroxide adjuvant to improve immunogenicity. The vaccine needs 2 doses, and the interval between the two doses is recommended to be ≥3 weeks, and the second dose should be completed as soon as possible within 8 weeks.

An adenovirus vector vaccine

Produced by Kangxinuo Bio-Co., Ltd., the principle is to recombine the spike glycoprotein (S protein) gene of the new coronavirus into the replication-deficient human adenovirus type 5 gene, and the recombinant adenovirus expresses Covid-19 S protein antigen in vivo to induce immune response, and the vaccine only needs one dose.

A recombinant subunit vaccine

Produced by Anhui Zhifeilong Kema Biopharmaceutical Co., Ltd., the principle is to recombine the new coronavirus S protein receptor binding region (RBD) gene into China hamster ovary (CHO) cell gene, express it in vitro to form RBD dimer, and add aluminum hydroxide adjuvant to improve immunogenicity.

The vaccine needs 3 doses, and the interval between two adjacent doses is recommended to be ≥4 weeks. The second dose should be completed within 8 weeks after the first dose, and the third dose should be completed within 6 months after the first dose.

Point sharing

Point collection

Click like

Original title: "One COVID-19 vaccine hits 2 people, is it wrong? Guangdong CDC responded! 》

Read the original text

Motive to Reform and Vitality to Innovation —— Strong Voice from Boao Forum for Asia Annual Conference in 2018

  Focus of annual meeting

  Want power from reform and vitality from innovation.

  — — Strong voice from the 2018 annual meeting of Boao Forum for Asia

  Guangming Daily reporter zhang yi Cao Yuanlong

  Born because of reform and opening up, prospered because of reform and opening up — — Boao is the easiest place to touch the pulse of reform and opening up.

  Boao Forum for Asia, let the world hear the strongest voice of China’s reform and opening up: In 2013, the Chairman of the Supreme Leader said in his keynote speech at the annual meeting of Boao Forum for Asia that "we will persist in reform and opening up"; In 2015, the Chairman of the Supreme Leader emphasized at the annual meeting of Boao Forum for Asia that "reform and opening up will be deepened more firmly".

  Boao Forum for Asia will witness the resurgence of the spring tide of reform and opening up and set sail. This year coincides with the 40th anniversary of China’s reform and opening up. The Chairman of the Supreme Leader was invited to attend the annual meeting of Boao Forum for Asia and will deliver an important speech, summarizing and combing the 40 years of China’s reform and opening up, and charting the future direction.

  Wanghai: The past and the future meet here

  "Reform and opening up" is the biggest hot spot of the 2018 annual meeting of Boao Forum for Asia.

  Facing the gate of the main venue of Boao Forum for Asia, the visual exhibition commemorating the 40th anniversary of China’s reform and opening up with the theme of "New Era and New Journey" has made people walk through 40 years in light and shadow.

  In Boao, reform and opening up are China and the world in the minds of foreign guests — — Chris Marin, president of American Lena International Company, told Guangming Daily that China’s development in the past few decades has benefited from reform and opening up. The reform and opening up has created a huge market in China, which has benefited the American business community a lot. It can be said that reform and opening up are also beneficial to Sino-US relations.

  In Boao, the reform and opening up is the global thinking of China scholars — — Gu Xueming, president of the Institute of International Trade and Economic Cooperation of the Ministry of Commerce, said: "In a sense, the current economic globalization is facing challenges and may also require worldwide reform and opening up. China’s practice in the past 40 years can provide some useful lessons."

  The reform and opening up not only brought epoch-making changes to China, but also had a great impact on the world. China has become the second largest economy in the world. Since the 18th National Congress of the Communist Party of China, comprehensive deepening of reform has broken down the institutional and institutional obstacles that hinder development, and 360 major reform plans and more than 1,500 reform measures have been introduced, making China develop vigorously and generate.

  Wang Yi, State Councilor and Foreign Minister, revealed that the keynote speech by the Supreme Leader at the Boao Forum for Asia will give the most authoritative explanation on China’s great achievements in reform and opening up, its important experience and enlightenment, its world significance and influence, and how China will promote opening up, deepen reform and start again in the new historical moment.

  Watching the tide: China will start again after reform and opening up

  "Foreign friends and guests from all walks of life want to perceive the direction of China policy in the new era and find their own development opportunities. This annual meeting of Boao Forum for Asia will be a very good window." Yang Xiyu, executive vice president of Boao Forum for Asia Research Institute, said.

  In the 2018 New Year message, the Chairman of the Supreme Leader emphasized that reform and opening up is the only way for the development and progress of contemporary China and the only way to realize the Chinese dream. We should take the opportunity of celebrating the 40th anniversary of the reform and opening up to the outside world, open the way on every mountain, bridge the gap when encountering water, and carry out the reform to the end.

  In the past five years, the changes in China have been profound and fundamental. The main contradiction in our society has been transformed into the contradiction between the people’s growing need for a better life and the unbalanced development. Socialism with Chinese characteristics has entered a new era, facing many new tasks and challenges.

  The reform and opening up since 1978 is a key measure to determine the fate of contemporary China. Forty years later, China planned and promoted reform from a higher starting point. Different from the state of "crossing the river by feeling the stones" 40 years ago, today’s reform in China has entered the fast-flowing deep water area, and it is going to step into an "upgraded version" led by top-level design. The new policy signals released at the Boao Forum for Asia will surely attract the attention of the world.

  Dai Xianglong, former governor of the People’s Bank of China, said at the sub-forum of "Asian Economic Forecast" of Boao Forum for Asia held on April 9th that the speed of economic growth in China is not as high as before, but the quality of growth is improving. After 40 years of reform and opening-up, along with GDP growth, environmental improvement, efficiency improvement, income increase and changes in the development stage, China won’t simply pursue speed in the future, but it doesn’t want speed, but it needs quality speed. "In the next 20 years, even by the middle of this century, Asia will still be the fastest growing region in the world, and the very important reason is the strong development of China. To achieve high-quality growth in China’s economy, it is necessary to carry out structural reforms on the supply side, vigorously cultivate new kinetic energy, and eliminate backward production capacity. " Dai Xianglong said.

  "The open door of China will never be closed, it will only grow bigger and bigger."

  "China will be more open and benefit the world to a greater extent."

  Entering a new era, China has embarked on a new journey of further going to the world and developing a higher-level open economy. It is embracing the world with an unprecedented open attitude and bringing more confidence to the world. Boao Forum for Asia will convey China’s determination to deepen reform and open wider to the outside world and China’s voice to the world.

  Sailing: innovation adds vitality to world development

  On the afternoon of the 9th, Boyaxuan, Boao Forum for Asia International Conference Center.

  "Welcome to Boao Forum for Asia!" The welcome language of the intelligent question-answering robot Xiao I attracted Joel Rue, chairman of the French "Bridge" think tank, to stop and interact: "Hello Xiao I, nice to meet you." After asking and answering questions, Lu Ai was amazed at China’s achievements in scientific and technological development. He told reporters that China’s scientific and technological innovation ability has made rapid progress, which has played a very good role in boosting economic development.

  Innovation is the first driving force of economic development. Turning over the meeting schedule of this Boao Forum for Asia, innovation is a hot topic that cannot be ignored. Sub-forums such as future transportation, future production, future communication, digital economy: the value of wisdom and a new round of technological revolution are colorful.

  What will the traffic be like in the future? He Xiaopeng, chairman of Xpeng Motors, believes that the future transportation is actually the improvement of efficiency, whether it is car or railway, whether it is air or space travel, it is the improvement of travel radius for users. Today, all technical policies and entrepreneurial actions are making efforts to this end. Liu Hualong, chairman of CRRC Group Co., Ltd. added that in addition to high efficiency, the future traffic should also include green, wisdom and harmony, which are the direction of future traffic tracks.

  In the future production, how will machines and people coexist? Richard edmondson Bailey, president of Hewlett-Packard Asia-Pacific, said that innovation comes from human beings, not some computers. In the future, some jobs will be replaced by machines, but such changes will take time and everyone will have the opportunity to receive corresponding education and training. Dong Mingzhu, chairman of Gree Electric, said that people are the greatest in any era. It is impossible to grow without hard work, so challenge is our eternal topic.

  Of course, innovation is comprehensive innovation. Participants believe that comprehensive innovation means not only scientific and technological innovation, but also institutional innovation. Only comprehensive innovation can truly inspire inexhaustible motivation.

  Pakistani Prime Minister Abasi said that Asian countries have been integrating in the fields of economy, trade, technology and energy in recent years, and they need the guidance of openness and tolerance. With reform, opening up and innovation, Asia has created many economic miracles and become the most dynamic region in the world. In the future, it needs more power and vitality from reform, opening up and innovation.

  Boao quick tour

  China is going further to the world and developing an open economy at a higher level. Boao Forum for Asia will convey China’s determination to deepen reform and open wider to the outside world and China’s voice to the world.

  The Asian Media Summit was held on April 9th. More than 140 heads of mainstream media from 40 Asian countries, as well as more than 300 representatives of Asian cultural scholars and relevant parties attended the opening ceremony.

  (Guangming Daily, Boao, Hainan, April 9 th)

It’s worth a look to read the column "China and the World Xinhuanet" in the great changes!

  Xinhuanet Beijing, January 30th (Reporter Xue Bili) The annual release ceremony of China Positive Energy "Five Hundred" network products sponsored by the Central Network Information Office was broadcast live on CCTV-1 and the network platform on the 28th, and the results of the 2021 China Positive Energy "Five Hundred" network products selection were announced simultaneously. After initial evaluation, re-evaluation, online voting exhibition and final evaluation, Xinhuanet won 25 awards, among which "On the World" column and "China’s Choice" won the excellent prize of "Network Positive Energy Special Topic" and "Network Positive Energy Animation Audio and Video" respectively. These two works are masterpieces of Xinhua Net’s creative exploration in the field of international reporting in recent years.

  At present, the international public opinion environment is extremely complicated and the struggle situation is becoming increasingly severe. In the complicated international public opinion field, how can China give a strong guiding voice? The "Five Hundred" network positive energy boutique selection activity has demonstrated for us. Among the outstanding works of "Five Hundred" publicized, Xinhuanet’s "On the World" column is unique.

  "On the World" column page (click to watch)

  The column "On the World" is the first international in-depth report column on the media state created by Xinhuanet. Since its inception in 2018, this column has relied on the annual international seminar on "Talking about the World" held by Xinhuanet to aggregate the resources of top domestic expert think tanks. Through the "combination boxing" mode of "efficient linkage of expert resources and innovative expression of daily reports", it has authoritatively and vividly interpreted the diplomatic thoughts of the supreme leader, commented on major international hot events from various angles, thoroughly guided the mainstream public opinion at home and abroad, and violently clarified and refuted the wrong views concerning China.

  In recent years, the column has endowed international topic reports with the characteristics of youthfulness and grounding through diversified media reports such as micro-videos, cartoons, posters and sharp comments, and launched a series of high-quality works with sharpness, strength and depth. For example, a series of reports on "Creative Poster | Democracy is not Coca Cola" which started with American hegemonic acts and exposed American "double standards"; Connected experts directly poke the pain points of the United States and the West, and the series of fusion reports of "Please look in the mirror"; The creative micro-video "Brothers are Far Away", which tells the story of China-Africa friendship.

  Expose and criticize the creative cartoon of "American democratic farce" about hypocritical human rights and democracy in the United States.

  Some experts praised that the column "On the World" has become a well-recognized brand product in overseas Chinese public opinion field, and is deeply loved by netizens at home and abroad.

  The award-winning video "China’s Choice" is one of the representative works of the column "On the World". With "choice" as the key word, the work tells the story from a small perspective through lofty and vast conception, unique narrative and magnificent visual effects. Under the background of a hundred-year change and the COVID-19 epidemic, China’s diplomacy is led by the diplomacy of the head of state, and it takes on the mission of facing difficulties and braving the wind and waves. Countless ordinary Chinese has chosen the spirit of fearless danger and boundless love. With the technique of knowing things from a small perspective and progressing step by step, the works convey the correct views and temperature feelings of China’s diplomacy, and show China’s heroic spirit and great country’s responsibility.

  Micro-video "China’s Choice"

  Connect China and foreign countries and communicate with the world. Through the excellent works in the column "On the World", we can let the world listen to China and understand China in a complicated crowd, guide netizens at home and abroad to understand China’s diplomacy and the world situation, and convey China’s "positive energy" to the world!

How does HPV spread?

Original Xu Chao, I’m Chaoski.

After talking about "cauliflower" for so long, the old readers who pay attention to me can be said to be very familiar with it. However, there are still many hin people coming to ask questions about sharp tips every day.

Today, I will tell you enough about condyloma acuminatum once.

Now, if you see friends here, please sit up straight and put down your legs. Let’s begin our little class.

What is condyloma acuminatum?

Condyloma acuminatum, also known as "anal genital warts", usually manifests as soft papules or patches on the external genitalia, perianal skin, perineum or groin.

HPV is a kind of naked double-stranded DNA virus without envelope, belonging to the family Papillomavirus.

At present, among more than 200 subtypes of HPV that have been identified, more than 40 subtypes can spread through sexual contact and infect the anal genital area.

According to the carcinogenicity, HPV is divided into high-risk type and low-risk type. 90%-95% of condyloma acuminatum cases are caused by low-risk HPV types 6 and 11 [1,2].

How is condyloma acuminatum spread?

Human is the only natural reservoir of HPV, and the infected person is the source of HPV infection. There are many HPV in the genital skin mucosa, which is the repository of HPV and the source of virus transmission.

HPV spreads through contact with infected skin or mucosa, and the virus invades epidermal basal cells through tiny scratches. Verruca is not necessary for virus transmission, but it is highly contagious because of its high viral load.

Transmission route

1. Sexual transmission: it is the most important route of transmission, and skin-mucous contact in heterosexual or homosexual sex can cause infection [3].

2. Vertical transmission: It is common for mothers infected with HPV in reproductive tract to transmit it to newborns through placenta and yindao delivery. For example, recurrent papilloma in children’s respiratory tract may be caused by children infected with HPV6/11.

3. Indirect contact transmission: A small number of patients may get sick through non-sexual contact infection. According to some data, 10% of women were infected with HPV before they lived in apricot [4], suggesting that contact between mouth and hands and raw zhi devices can also infect HPV.

HPV infection can enter the incubation period without obvious symptoms and signs. The incubation period is usually 3 weeks to 8 months, with an average of 3 months. Studies have shown that in patients with condyloma acuminatum after new HPV infection, the median time from the detection of HPV6 or HPV11 to the discovery of condyloma acuminatum is 2.9 months [5].

What are the clinical manifestations and symptoms after being infected with condyloma acuminatum?

Appearance and texture: At the initial stage, the lesions of condyloma acuminatum showed local small papules, which gradually increased or increased from the needle to the millet size and spread to the surrounding area. The wart body can be single or multiple, and it can be papillary, cockscomb-shaped, cauliflower-shaped, flat, dome-shaped, filamentous, mushroom-shaped, pedicled, cerebral gyrus-shaped, plaque-like, smooth (especially on penis body) and so on. Condyloma acuminatum is soft to the touch, ranging from 1mm in diameter to several centimeters in size.

Color: Warts vary in color, ranging from pink to crimson (non-keratinizing lesions), gray (severe keratinizing lesions), brown-black (pigmented lesions) and violet.

Location: For boys, condyloma acuminatum mainly occurs in prepuce, Gui head, coronary sulcus, frenulum, Penis, urethral orifice, perianal region and scrotum. Girls are more likely to occur in Labia, urethral orifice, Vagina mouth, perineum, Vagina wall, cervix and perianal region. If anal sex occurs, warts may appear in the perianal region, anal canal and rectum for the recipient. In addition, if oral sex is performed, warts may also appear in the mouth.

Symptoms: There are generally no symptoms after being infected with condyloma acuminatum, which is one of the reasons why many people do not pay attention to or even delay treatment. A few people may have itching, foreign body sensation, pressure or burning sensation. Due to the increase of brittleness of skin lesions and friction, the skin is broken, soaked, eroded, bleeding or secondary infection, resulting in special odor. In addition, female patients may have increased vagina secretion.

Because condyloma acuminatum is easy to recur, or the warts affect daily life, patients often feel shame, social isolation, anxiety, depression, fear and guilt, and they are also worried that condyloma acuminatum will affect future fertility and increase cancer risk.

In addition, condyloma acuminatum also has a great influence on the feelings between sex partner, which may lead to family conflicts and even lead to the breakdown of relationships.

How to diagnose condyloma acuminatum?

Generally speaking, most patients infected with condyloma acuminatum may have contact history, such as multiple sexual partners, high-risk apricot behavior, or sexual partners with infection history, or close indirect contact history with patients with condyloma acuminatum, and so on. Through these medical histories, combined with the typical clinical manifestations of condyloma acuminatum, the diagnosis can be basically made through face-to-face diagnosis.

For those who cannot be clearly diagnosed by face-to-face examination, they can also be diagnosed by auxiliary examination [6].

1. Acetic acid white test: 3%-5% acetic acid solution is wet-applied or coated on the lesion to be examined and the surrounding skin mucosa. Within 3-5 minutes, if you see a uniform whitening area, it is a positive reaction.

2. Dermatoscope: Dermatoscope can non-invasively, quickly and clearly identify skin lesions, hyperplastic blood vessels and structures that cannot be recognized by naked eyes. Many literatures at home and abroad reported that the diagnostic rate of atypical condyloma acuminatum and tiny condyloma acuminatum by dermatoscope was over 90%.

3. Nucleic acid amplification test: HPV in skin lesions was detected by amplifying HPV-specific genes (L1, E6, E7 region genes), and nucleic acid detection methods included polymerase chain reaction (PCR), real-time fluorescence PCR, and in-situ hybridization test with nucleic acid probes.

4. Pathological examination: For typical skin lesions, histopathological biopsy is unnecessary. If there are some conditions such as uncertain diagnosis, pathological examination can be performed.

In addition, for condyloma acuminatum in anus, vagina and urethra, anoscope, colposcope and urethroscope may be needed for auxiliary examination.

How should condyloma acuminatum be treated?

If you are unfortunately infected with condyloma acuminatum, don’t panic, go to the dermatology department of public hospitals as soon as possible, and sometimes go to urology (boys)/gynecology (girls) for treatment.

The purpose of treating condyloma acuminatum is to remove the wart as soon as possible and eliminate the subclinical infection around the wart as much as possible to reduce or prevent recurrence.

Some people found out that the other person had warts after apricot behavior, and asked if they could use blocking drugs. Unfortunately, there are no blocking drugs for HPV (HIV has related blocking drugs).

Not only are there no blocking drugs, but there are no effective antiviral drugs against HPV at present, so it is impossible to eradicate HPV infection by systematic application of antiviral drugs [7].

If you find yourself growing warts, you can use drugs, physics, surgery, chemistry and other methods to remove them. However, at present, there is no definite evidence to show which treatment scheme is superior to other schemes, and no treatment scheme is suitable for all patients and all warts. All treatment methods have a certain recurrence rate.

According to the suggestion of Clinical Diagnosis and Treatment Guidelines for Condyloma Acuminatum in China (2021 Complete Edition), "The treatment of condyloma Acuminatum can be based on the size, number, location and shape of wart, the patient’s wishes, economic conditions and adverse reactions, and fully consider the individual differences of patients’ age, immune status and compliance, etc." [6].

Drug treatment includes: 0.5% podophyllotoxin tincture, 5% imiquimod cream, 80%-90% trichloroacetic acid solution and so on.

Physical therapy includes: cryotherapy, laser therapy, ionization and high frequency electrotome therapy, etc.

If the number of warts is small, pedicled or large, shearing and excision can be used under local anesthesia, supplemented by electrocautery to destroy the residual warts and control bleeding, without suture.

Photodynamic therapy is suitable for removing small warts and basal therapy after physical therapy to remove large warts. It can be used for the treatment in the cavity such as anal canal, urethral orifice, urethra and cervical canal.

Recurrence and cure

After treatment, condyloma acuminatum is cured by the disappearance of wart body.

However, the recurrence rate of condyloma acuminatum is very high, and the recurrence rate reported by different documents varies greatly, ranging from 10% to 70%. The recurrence rate is the highest within 3 months, and it gradually decreases with time.

At present, most scholars believe that if condyloma acuminatum does not recur after 6-9 months of treatment, the chance of recurrence will be reduced.

Although the recurrence rate of condyloma acuminatum is high, don’t think that you have a "terminal disease" after infection, but have confidence in the treatment.

How to prevent condyloma acuminatum?

Want to prevent condyloma acuminatum, in fact, it is not difficult, four words: "totally".

For people who have no apricot life, there is basically no need to worry about whether they will be infected with condyloma acuminatum. You know, avoiding apricot life is the most reliable way to prevent genital HPV infection.

If you want to have apricot behaviors, don’t engage in unsafe and high-risk apricot behaviors, such as making fire contracts and commercial apricot behaviors. Limiting the number of sex partner can reduce the risk of condyloma acuminatum.

In addition, wearing condoms in apricot life can also prevent condyloma acuminatum to some extent. However, wearing a condom may not be able to protect you, because you may also be infected with HPV in places that are not covered by condoms [8]. Don’t think it’s really safe to wear a condom when unsafe apricot behavior occurs. The safest thing is to avoid high-risk apricot behavior.

Vaccination with HPV vaccine can also prevent HPV infection, and tetravalent or nonavalent HPV vaccine can prevent 90%-95% of condyloma acuminatum. However, if you have been infected with HPV or have grown condyloma acuminatum, it is useless to vaccinate.

I’ve talked so much, I don’t know if you can read it carefully. Mainly because I have received too many inquiries about condyloma acuminatum, I sincerely hope that everyone can protect themselves and others and be healthy.

It’s not easy to write. Don’t you give a "like" or "watching" when you pass by?

references

[1] GARLAND S M, STEBEN M, SINGS H L, et al. Natural history of genital warts: analysis of the placebo arm of 2 randomized phase III trials of a quadrivalent human papillomavirus (types 6, 11, 16, and 18) vaccine [J]. J Infect Dis, 2009, 199(6): 805-14.

[2] BALL S L, WINDER D M, VAUGHAN K, et al. Analyses of human papillomavirus genotypes and viral loads in anogenital warts [J]. J Med Virol, 2011, 83(8): 1345-50.

[3] WRIGHT T C, JR. Natural history of HPV infections [J]. J Fam Pract, 2009, 58(9 Suppl HPV): S3-7.

[4] TAY S K, HO T H, LIM-TAN S K. Is genital human papillomavirus infection always sexually transmitted? [J]. Aust N Z J Obstet Gynaecol, 1990, 30(3): 240-2.

[5] WINER R L, KIVIAT N B, HUGHES J P, et al. Development and duration of human papillomavirus lesions, after initial infection [J]. J Infect Dis, 2005, 191(5): 731-8.

Dermatology and Venereology Branch of Chinese Medical Association, Dermatologist Branch of Chinese Medical Association, Dermatology and Venereology Committee of Chinese Rehabilitation Medical Association. Clinical diagnosis and treatment guidelines for condyloma acuminatum in China (2021 full edition) [J]. chinese journal of dermatovenereology, 2021, 35(4): 359-74.

[7] WORKOWSKI K A, BOLAN G A, CENTERS FOR DISEASE C, et al. Sexually transmitted diseases treatment guidelines, 2015 [J]. MMWR Recomm Rep, 2015, 64(RR-03): 1-137.

[8] GILSON R, NUGENT D, WERNER R N, et al. 2019 IUSTI-Europe guideline for the management of anogenital warts [J]. J Eur Acad Dermatol Venereol, 2020, 34(8): 1644-53.

Disclaimer: Some pictures are from the Internet. If there is any infringement, please contact to delete them.

-End of this period-

Read the original text

Domestic large four-engine UAV successfully made its first flight.

  A few days ago, at Fengming Navigation Airport in Zigong, Sichuan, a large-scale four-engine drone codenamed "Double-tailed Scorpion D" entered the runway independently and took off smoothly. After flying for 18 minutes, it landed smoothly, and the whole flight was trouble-free. The first flight was a complete success.

  This type of UAV is a large-scale four-engine UAV independently researched and developed in China, with complete intellectual property rights. It has larger loading space, heavier loading capacity, stronger power support and higher system reliability and flight safety. It can carry more high-performance mission loads and perform support tasks such as freight logistics, aviation broadcasting and mission load use.

  This time, the large-scale four-engine UAV achieved its first flight, further enriching the application scenarios of commercial large-scale UAVs, and also marking that China’s large-scale UAV industry has the ability to quickly develop and respond to different market needs. "Double-tailed Scorpion D" will be transferred to Zhuhai after its successful first flight, and will be unveiled at the upcoming 14th China Air Show.

  Reporter: Xue Chen.

  Produced by Audio and Video Department of Xinhua News Agency

BYD took the "Eye of the Gods" to make a scene and drove the industrial chain into a key supplier "Little Partner" to actively follow up.

  China Securities Network News () All models are equipped with "Eye of God" advanced intelligent driving, which is regarded as further expanding the competitive advantage. The reporter was informed that Geshi Automobile Research Institute has raised BYD’s sales forecast in 2025. At the same time, some brokers also believe that BYD is expected to start a new round of strong product cycle.

  As a directly related field, the intelligent driving industry chain has recently performed well in stock prices. Sagitar Juchuang, Hesai Technology and other companies have disclosed the progress of cooperation with BYD in smart driving. If BYD can further develop with the strategy of standard smart driving, core suppliers such as Li Yuan Heng are also expected to catch the "express train".

  Smart driving standard expands BYD’s advantages

  A few days ago, BYD announced that all models will be equipped with the "Eye of the God" high-level intelligent driving, and all models above 100,000 yuan will be standard, and most models below 100,000 yuan will be equipped. The first batch of 21 models will be listed. In addition, BYD announced that the Xuanji architecture will be fully connected to DeepSeek to enhance AI capabilities.

  In response to the above news, Goldman Sachs commented in its latest report that BYD has once again widened the technical gap with most automakers in the market and further enhanced its competitive advantage among peers through the large-scale introduction of autonomous driving function to mass-market models.

  Wang Xianbin, vice president of Geshi Automobile Research Institute, told reporters that BYD has successfully attacked the entry-level models of joint venture brands through the strategy of "the same price of oil and electricity" and "electricity is lower than oil". A few days ago, BYD launched the strategy of high-end intelligent driving as standard, which is essentially "increasing the quantity without increasing the price" and expanding the price war from explicit to implicit.

  The above-mentioned people further stated that even if we don’t talk about the technicality of the "Eye of the God" high-level intelligent driving, BYD has achieved the pattern of "no one has me" through the standard of the whole department, and further distanced itself from its competitors, especially for the joint venture entry-level models.

  Guosheng Securities believes that BYD, as a leader in new energy sales, has obvious scale advantages and is expected to further reduce the cost of intelligent driving configuration. Under the background of technological innovation and cost advantage, the company is expected to start a new round of strong product cycle.

  Wang Xianbin is also optimistic about the impact of smart driving standard on BYD’s sales. He said that based on BYD’s strong competitive advantage, Geshi Automobile Research Institute raised BYD’s sales forecast of new energy vehicles in 2025, with the main increase brought by entry-level models.

  The intelligent driving industry chain has attracted much attention.

  "In the past, we used the penetration rate of new energy vehicles to measure the speed of industry development. Starting this year, we should use high-level smart driving to promote the high-quality development of the industry. " In Wang Chuanfu’s view, 2025 will be the first year of intelligent driving for all. He said that buying a car to see smart driving in 2025 will become an indispensable configuration in the next two to three years. At that time, cars without safe smart driving will become a minority.

  Robin Li, founder of Baidu, said at the World Governments Summit 2025 held in Dubai, United Arab Emirates that Robotaxi can greatly reduce the death rate of traffic accidents. Judging from the actual record of radish running, the accident rate is only 1/14 of that of human drivers. The equal rights of smart driving will set off the competition of comprehensive cost performance of mainstream products in China automobile market in 2025, and further lower the technical threshold of smart driving.

  Guotai Junan Research Report shows that "Eye of the God" comes out and is optimistic about the industrial chain of intelligent driving lidar. It is understood that BYD’s "Eye of God" platforms A and B will be equipped with lidar. With "intellectual driving and equal rights" becoming an important trend in the development of the industry, the laser radar industry may usher in a new round of outbreak.

  At the same time, the market expects that as the price of lidar continues to drop, more and more models with lower prices will come standard with lidar in the future.

  The reporter learned that at present, the lidar carried by BYD’s medium and high-end smart driving scheme is mainly supplied by Hong Kong stock company Sagitar Juchuang, accounting for more than 80%, involving 11 models. In addition, BYD’s upcoming two new cars, Sea Lion 07EV Intelligent Driving Edition and Song LEV, are equipped with Sagitar Juchuang lidar.

  According to the announcement of Wo Sai Technology on February 11th, the company will deepen its cooperation with BYD in intelligent driving, and will soon enter the stage of mass production. In 2025, BYD’s more than ten models will be equipped with Hesse lidar.

  In terms of smart driving solutions, () on the interactive platform, the cooperation between the company and BYD includes the most cost-effective smart driving solutions, data compliance, high-precision positioning, car-level chips and many other fields. Among them, the smart driving solution has been mass-produced and shipped to a scale of 1 million units. According to the current fixed-point order statistics, it will accompany its domestic and foreign models to mass-produce and go to sea in the above-mentioned directions, and continue to help the industry’s high-level smart driving enter the era of equal rights.

  It is worth noting that intelligent driving has other technical paths. For example, Tesla does not use any sensor except the camera, adopts a pure vision scheme, and relies on neural networks and algorithms to gradually transition from assisted driving to fully automatic driving, and finally to a completely unmanned stage.

  Supplier "small partners" actively follow up.

  In addition to the laser radar link that is most directly affected in the smart driving scheme, several BYD suppliers have updated their cooperation with BYD. Due to the optimistic sales expectation brought by BYD’s smart driving standard, the supplier "small partner" is expected to "catch up" with BYD’s rapid development.

  The reporter learned from Li Yuan Heng that Li Yuan Heng has established a strategic cooperative relationship with BYD since 2014, and jointly signed a number of important agreements, such as Strategic Cooperation Agreement for Automation Equipment and Cooperation Agreement for Preferred Suppliers, and became its core supplier. Up to now, the company has provided BYD with high-end equipment or automated production lines in many fields, including power lithium batteries, consumer lithium batteries, intelligent storage and auto parts, and delivered them to 40 bases in 18 provinces in China and overseas bases in Brazil and Hungary.

  In the recent interactive platform or investor relations activity record, many companies also responded to the cooperation with BYD.

  "The company’s data cable products include 10 Gigabit Ethernet cables, coaxial cables and other products. In recent years, some of the company’s data cable products have been applied to various models of BYD. " () Said on the interactive platform.

  Yu Taiwei said in the record of investor relations activities that in terms of vehicle data transmission, the company can choose to use 100 megabits or gigabit physical layer chip products according to the requirements of different intelligent driving systems for data volume and transmission speed, and it has been applied to BYD’s Looking Up and Tengshi series. At the same time, the company’s car Ethernet switch chip has also been jointly tested at the client, and it is expected to be sold to customers in complete sets with the car Ethernet physical layer chip in the future.

  In addition, () on the interactive platform, BYD is currently supplied with color-changing skylight glass intelligent controllers and high-voltage electrical distribution modules, etc. In the future, the company will actively explore customers and products and obtain more new high-quality projects. (Li Zijian)

Allen, this time it’s a black man!

  The writer of this article is @ Yili of Xiaowan family.

  Tsui Hark’s Hidden Girl

  Your brother Guo Chao’s new dramaTwilight white firstFinally went online yesterday.

  Explain for passers-by who don’t know the truth first."Who is Guo Chao?"

  Guochao, that isAllen. Because his original name was Ren Guochao, everyone called him "Guo Chao, Guo Chao".

  Since 2017, when a film "Glory of Datang" was born, he became famous as Li Chu, the king of Guangping, and was regarded as a strong competitor of the first student in ancient costume and the owner of cosmetic acting.

  Ren Jialun’s new costume novel "Twilight White Shout", which has been long awaited by many drama fans, is adapted from the original novel "Cangxuelong Singing Twilight White Shout" by screenwriter Han Peizhen.The martial arts version of "Romeo and Juliet"

  Allen is divided into two corners, namely Lin Jing, the master of Long Yincheng’s unfamiliar words, and Na Lan Yue, the master of Ling Xuge’s less pavilion with unfathomable martial arts.

  Zhang HuiwenRong Yan, who plays the role, is the second young lady of Long Yincheng and the most precious daughter of Rong Jingfeng, the Lord of the city.

  Rong Chen and Lin Jing fell in love, and they also wanted to help the world hand in hand, looking for the lost healing instrument Chihuazhu, but they were caught between Scylla and Charybdis-

  There is a family feud and old hatred between the two sides, and a young lady named Rong rewelding (whitehairpin) who is eyeing up, and there are evil spiritual teachings and a group of minions outside.

  People who are familiar with Allen’s road to performing arts must know that he has always had a dream of loving beans in his heart. He wanted to be a singer and dancer, but in the end he became angry because of his status as an actor.

  He hasn’t had time to realize his dream, but his role in "Twilight White Shout", Na Lanyue, has taken the lead in the martial arts, and officially made his debut in Longyincheng with the stage name "Lin Jing".

  Next, let’s take a look.Nalan Yue aka Lin Jing’s Business Road, the Black-bellied Son……

>

  Be a male classmate with a story.

  If Longyin City is a stage, the way that Lan Yue made her debut can be said to be very fascinating-He ran away from marriage.

  Because of his distinguished family background and many enemies in the Jianghu, he gave himself a "stage name" called Lin Jing to save his life.

  Lin Jing, who escaped from marriage, was placed under the fence of Longyin City.On the surface, he is a "social animal" who tries to escape from boring daily life even in the face of family opposition.Jumping from one fire pit to another, even in Longyin City, you should pick up your tail and be a man.

  It’s really easy for girls to feel pity for such a poor boy and want to help him escape from the shackles and realize his dreams.

  butIn fact, Lan Yue, who is hidden behind the identity of "Lin Jing", is a real childe and a prominent figure in the Jianghu..

  Although he deliberately hides his true identity, everyone will not be willing to blame him as long as they know the difficulties.

  This kind of contrast will become a charm.

>

  Excellent professional ability

  If Longyincheng is a stage, Lin Jing’s business ability is not the best, but it is definitely excellent.

  After all,This is a man who can hang Lord Bailaotang, who is Rong Jingfeng’s right-hand man, upside down and rush to call the master..

  This means that, at the very least, Lin Jing’s martial arts is absolutely above the white old master whose qualifications are n times that of him.

  And don’t forget, at the beginning of "The Beauty at Dusk", Rong Yan was ambushed by an unknown killer while escorting Chihuazhu back to Longyin City. At the height of the fight, Lin Jing saved her.

  What’s more, he seems to have used less than half success.

  The above is the part of armed confrontation. Lin Jing’s level is already excellent. In addition,His martial arts are also very ornamental..

  There is a fencing teaching scene in the rain … Don’t get me wrong, it’s not that Lin Jing personally went off to teach the apprentice Bai Laotang to dance the sword, but that he taught the little disciple Sun Rong (she studied under Bai Laotang) fencing.

  At this time, the two people who haven’t fallen in love, under the guidance of Lin Jing, still dance the sword beautifully and beautifully.

>

  Treat the opposite sex appropriately.

  If Longyin City is a stage, then Lin Jing has an official position, and that is Rong Yan.

  In order to maintain the CP sense of the official pairing and treat other members of the opposite sex, he kept an excellent distance and was very measured.

  As mentioned earlier, Lan Yue turned into Lin Jing’s opportunity-running away from marriage.

  When he faces his fiancé e, Miss Mei, who is set by his family, he will make it clear for three times that he has a heart, so as not to let the girls misunderstand him, nor to let the other party have any illusions about himself.

  Miss Meijia is also a reasonable girl, who obediently gives up her fiancee’s position and wants to fulfill the happiness of her beloved.

  In order to dispel Rong’s worries and make the family dead and urge marriage, Nalan Yue, who returned to her original identity, designed a drama to steal dragons and turn them into phoenixes.

  In the name of concluding a contract with Miss Mei’s family, let her mother, who is the owner of Lingxu Pavilion but doesn’t know the truth, take Rong Chen to the scene to watch the ceremony.

  Just when everyone thought that they were going to worship heaven and earth, the high hall and the husband and wife, they directly threw out the answer to the play. It turned out that he and Miss Mei were sworn brothers, not meeting the bride!

  Nalan Yue’s mother Lin Ruohan

  In this way, we can not only win over the Mei clan, but also get away with it in this marriage of parents’ orders, and continue to do official matching with Rong Chen naturally. What a clever man.

>

  Beautiful, strong and miserable

  On the stage of Longyincheng, Lin Jing’s appearance is attractive and his martial arts are superb, but he has few opponents, but he has been assassinated everywhere.

  Although the duke Rong Jingfeng seems to bring him under his command, he is very wary of this epigenetic whose origin is a mystery, and even has the selfishness of removing him.

  Miss Rong rewelding, who has a gloomy personality and a good force value, also doesn’t like him very much.

  Not to mention the spiritual teachings that regard him as a thorn in the side.

  It is also because Lin Jing can not only fight, but also use his brain very well. He often sees through Ming Zun’s tricks, so that the devil will not hesitate to kill him in 180 ways.

  In addition to these enemies on the surface, there are countless pairs of eyes staring at him in the Jianghu.

  Lin Jing, who is fooling around, is in such a difficult situation, not to mention his real self, Lan Yue.

  As a aristocratic family with red beads, Na Lanyue was destined to experience a bloody affair. Screenwriter, you are so cruel!

  However, this kind of personnel is very consistent with the first standard of "top flow"-Beauty, strength and misery.

  Nalan Yue, the leader of Wulin, sounds like a good name.

>

  Be a beautiful young man with four stresses and five stresses.

  Although people can’t help themselves in the Jianghu, and there are few trustworthy people around them, both Lin Jing and Na Lan Yue maintain a childlike heart, which helps the world.

  Such a decent person can rest assured that he likes it.

  Can a "Wulin Top Stream" like Na Lanyue/Lin Jing impress you?

  Anyway, still want toGuo Chao’s ability to digest scriptsCall.

  Because of the setting of the characters in "Dusk White Head", it is a rare type of one person with two roles in his work list, and it needs to turn back and run between cynicism and deep talent in a very short time.

  Switching is as smooth as silk.

  Not much to say, the country is super-small.

  Note: Some pictures in this article are from Douban and the Internet. If there is any infringement, please contact us actively.

>

  [One-mile past article]

  Click to read

  Lady Gaga is also going to play "Black Widow"?

  This is this year’s Dear, Dear?

  No matter, Nana Komatsu × Suda Masaki is true!

>

>

A picture reading+interpretation of Q&A | Guidelines for preventing novel coronavirus from being infected with masks (April 2023 edition)

About printing and distributing the prevention of novel coronavirus infectionGuidelines for wearing masks by the publicNotice (April 2023 edition)

All provinces, autonomous regions, municipalities directly under the Central Government and Xinjiang Production and Construction Corps joint defense and control mechanism (leading group, headquarters), the State Council joint defense and control mechanism members:

In order to further improve the prevention and control of infection in novel coronavirus and guide the public to wear masks scientifically, the Epidemic Prevention and Control Group of the State Council Joint Prevention and Control Mechanism formulated the Guidelines for Preventing People from Wearing Masks in novel coronavirus (April 2023). Is issued to you, please earnestly organize the implementation. If all localities and departments have relevant suggestions in the implementation process, please give timely feedback to the epidemic prevention and control team.

The State Council joint defense joint control mechanism epidemic prevention and control zu

(On behalf of the National Bureau of Disease Control and Prevention)

April 12, 2023

(Information disclosure form: voluntary disclosure)

Prevention of novel coronavirus infectionGuidelines for wearing masks by the public(April 2023 edition)

Wearing masks scientifically is an important measure to prevent novel coronavirus infection. According to the requirements of "Overall Plan for Implementing" Class B Management "for novel coronavirus Infection" and "novel coronavirus Infection Prevention and Control Plan (Tenth Edition)", this guideline is formulated to guide the public to wear masks scientifically and effectively protect public health.

I. Situations or scenes where masks should be worn

1 novel coronavirus antigen or nucleic acid test positive period.

2. During the period when fever, sore throat, cough, runny nose, muscle aches, fatigue and other suspected novel coronavirus infection symptoms appear.

3. When a cluster epidemic occurs in the community or school where you live, work or study.

4. When going to a medical institution for treatment, accompanying, accompanying or visiting.

5. When migrants enter places where vulnerable people are concentrated, such as pension institutions and social welfare institutions.

6. During the work of public service personnel such as medical care, catering, cleaning and security in key institutions such as pension institutions, social welfare institutions and child care institutions, schools and off-campus training institutions.

Second, it is recommended to wear a mask.

1. When taking public transportation such as airplanes, trains, long-distance buses, ships, subways and buses.

2. When entering supermarkets, theaters, passenger stations and other places with closed environment and crowded people.

3. When the elderly, patients with chronic basic diseases and pregnant women go to indoor public places.

4. When a large-scale conference or activity is held with a wide source of participants, strong mobility and no prevention and control requirements such as nucleic acid detection or antigen detection and health monitoring.

Third, the common situation or scene of not wearing a mask

1. Outdoor places such as open-air squares and parks.

2. Indoor workplaces and meeting rooms with relatively fixed personnel.

3. When a large-scale conference or activity with a wide source of participants and strong mobility but with clear prevention and control requirements such as nucleic acid detection or antigen detection and health monitoring is held.

4. For specific personnel who regularly carry out nucleic acid detection or antigen detection and health monitoring, such as cast members of celebration activities and members of honor guards, when attending large-scale activities.

5. People who exercise may have difficulty breathing when wearing a mask.

Infants and young children aged 6.3 and under.

7. During the period of school teachers and students.

Fourth, mask selection

Novel coronavirus infected persons and suspected infected persons are advised to wear N95 or KN95 particulate protective masks or above (no breathing valve), while others are advised to wear disposable medical masks or medical surgical masks.

V. Other precautions

1. In addition to the above situations or scenarios, individuals can choose whether to wear masks according to their own health status and needs.

2. People with cardiopulmonary dysfunction should wear masks under the guidance of doctors.

3. The institution where the relevant public service personnel work shall equip them with masks that meet the relevant requirements, and set up an independent waste mask storage device.

This mask guideline will be dynamically optimized and adjusted according to the needs of epidemic prevention and control. All localities and departments can formulate local and industry mask guidelines according to local and industry realities and with reference to this mask guideline.

Guidelines on the prevention of novel coronavirus infection and public wearing masks(April 2023 edition) "Unscramble questions and answers

1. Why should the guidelines for wearing masks be revised?

During the period when novel coronavirus was infected with "Class B A tube", the state successively issued five editions of guidelines for wearing masks, which played an important role in protecting public health and effectively preventing and controlling the spread of the epidemic. On January 8th, 2023, the "Class B Management" was officially implemented for novel coronavirus infection, and the prevention and control work was fully transferred to the stage of "protecting health and preventing severe diseases", during which the public was encouraged to continue to adhere to good hygiene habits such as wearing masks. Thanks to the unremitting efforts of all parties, the country has achieved a smooth transition in epidemic prevention and control in less than two months and achieved a major decisive victory in epidemic prevention and control. At present, the epidemic situation in COVID-19 in China is generally sporadic, but the global epidemic situation is still prevalent and the virus strains are constantly mutating, so there is still the risk of epidemic rebound in China. According to the epidemic situation and the need of prevention and control in China, on the basis of the first five editions of the guidelines for wearing masks, we organized and formulated the Guidelines for Preventing People from Infecting novel coronavirus from Wearing Masks (April 2023 Edition) (hereinafter referred to as the Guidelines for Wearing Masks) to guide the public to wear masks scientifically and standardly.

2. What are the main revision considerations of the newly issued Guidelines for Wearing Masks?

First, considering the current epidemic situation and the harm changes in novel coronavirus, the suggestion of wearing masks was optimized and adjusted, which further reduced the situations or scenes where masks should be worn, and minimized the impact on public production and life on the basis of ensuring the prevention and control effect. The second is to focus on the guidance of the public to wear masks. For common situations and scenes closely related to public life, work, study, etc., the classification suggestions of wearing masks, suggesting wearing masks, and not wearing masks are put forward. The third is to adhere to the principle of dynamic optimization and adjustment. The Guidelines for Wearing Masks will be revised and improved according to the changes in the epidemic situation and the needs of prevention and control. All localities and departments can formulate local and industry mask guidelines according to local and industry realities, combined with the epidemic situation and referring to this mask guideline.

Third, which situations or scenes should wear masks?

There are three kinds of situations or scenes where masks should be worn: First, there are situations where there is a risk of epidemic spread, such as when the public is infected in novel coronavirus or when there are symptoms of suspected novel coronavirus infection. Second, it is in a situation or scene with high risk of infection, such as when there is a cluster epidemic in the community where you live, work or study, and when you go to a medical institution for treatment, accompanying, accompanying and visiting. Third, it is necessary to guard against situations or scenes in which the epidemic situation is imported into key institutions. For example, foreigners should wear masks when entering places where vulnerable people are concentrated, such as pension institutions, social welfare institutions, child care institutions, schools, off-campus training institutions and other key institutions. Public service personnel such as medical care, catering, cleaning and security should wear masks throughout their work to prevent the epidemic situation from being imported into relevant key institutions.

4. What situations or scenes suggest wearing a mask?

There are three main types of situations or scenes that suggest wearing masks: First, entering areas or places with large traffic or closed environment and crowded people, such as taking public transport, entering supermarkets, theaters, passenger stations, etc. Once there are novel coronavirus-infected people in the relevant areas or places, the epidemic will easily spread due to crowded people and poor ventilation. Second, the elderly, patients with chronic basic diseases, pregnant women and other special groups are more harmful after infection. When going to indoor public places, it is recommended to wear masks to strengthen self-protection. Third, it is a large-scale meeting or activity with a wide source of personnel and strong mobility. If the participants do not carry out nucleic acid testing or antigen testing and health monitoring, once the epidemic situation is imported, it is easy to have a cluster epidemic, and it is recommended to wear a mask.

5. What situations or scenes can you not wear a mask?

There are three main types of situations or scenes where masks are not needed: First, situations or scenes with low risk of infection, such as outdoor places such as open squares and parks, or indoor places and conference rooms with relatively fixed personnel. The second is the situation or scene where the risk of infection is effectively prevented, such as holding a large-scale meeting or activity, and detecting potential infected people in time by carrying out nucleic acid detection or antigen detection and health monitoring on the participants. The third is the situation or scene where the risk of infection is low and wearing a mask may have a certain impact on work, life and study, for example, infants aged 3 and below, school teachers and students during school and those who are exercising and wearing a mask may cause breathing difficulties.

Six, how to choose to wear the right type of mask?

In view of the high risk of epidemic spread among infected people and suspected infected people in novel coronavirus, it is suggested that they wear N95 or KN95 particulate protection masks or above (no breathing valve), while others suggest wearing disposable medical masks or medical surgical masks, and pay attention to changing masks in time.

Read a picture

Guidelines for the prevention of novel coronavirus infection and public wearing masks(April 2023 edition)

Source: National Bureau of Disease Control and Prevention.