One COVID-19 vaccine hits two people, is it wrong？ Guangdong CDC responded!
National Covid-19 vaccine
The vaccination work is being carried out in an orderly manner.
Recently,
When some citizens went to vaccinate, they found that,
A bottle of vaccine can be used by two people,
Is it the wrong number?
Is this standard operation?
On May 11th, Guangdong CDC responded: Don’t worry! This is a two-person packaged COVID-19 vaccine that has just come on the market, and one bottle can be used by two people.
△ Xinhua News Agency reporter Chen Zeguo photo
What is a two-person package?
COVID-19 vaccine?
Two-person package means that one vaccine can inoculate two people, and each bottle is 1.0 ml (dosage for two people), and the dosage for each person is 0.5ml. The vaccine packaged for 2 people is exactly the same as the vaccine packaged for 1 person, except that the packaging color and filling dose are different, which does not affect the individual vaccination effect.
In fact, many vaccines are packaged in multiple doses. For example, the BCG vaccine vaccinated in obstetrics at birth is packaged in five doses, the live attenuated polio vaccine (drops) in children’s immunization program is packaged in ten doses, the group A meningococcal vaccine vaccinated at the age of six months is packaged in five doses, and the diphtheria vaccine vaccinated at the age of six is packaged in four doses.
Therefore, whether it is the vaccination effect of the vaccine or the doctor’s operation technology, everyone does not need to worry, and can be vaccinated with confidence.
△ Source: Xinhua News Agency
2-person packaged vaccine
What are the advantages?
Vaccine supply guarantee is the key factor to actively and steadily promote vaccination in Covid-19. At present, the production capacity of Covid-19 vaccine in China is greatly influenced by filling and packaging. With the approval of relevant state departments, COVID-19 vaccine manufacturers will successively produce a single COVID-19 vaccine packaged for two people.
Two-person packaging can improve the production efficiency and supply of vaccines, so that more people can get vaccinated as soon as possible, especially suitable for large-scale vaccination at present.
2-person packaged vaccine
Do you want two shots, too?
Like the vaccination procedure for a single dose, the vaccine packaged for two people needs to be vaccinated twice in the whole process, and the interval between the two doses is suggested to be greater than or equal to 3 weeks (21 days), and the second dose should be completed as soon as possible within 8 weeks (56 days).
The first shot was a single shot,
Can the second injection be used for two people?
The Guangdong Provincial Center for Disease Control and Prevention said that it can be vaccinated. At present, all Covid-19 vaccines used in Guangdong are inactivated vaccines. If the first shot is inactivated vaccine, no matter whether the manufacturer is Beijing Kexing or China Bio, two doses of inactivated vaccine can be selected for the second shot.
△ Source: Xinhua News Agency
At present,
The national cumulative report of vaccination against Covid-19 vaccine.
It has exceeded 300 million doses!
However, on May 8th, Zhong Nanshan, an academician of China Academy of Engineering, said by video that China, as a populous country, has withstood the first stage of the epidemic since the COVID-19 epidemic occurred more than a year ago, but it can’t be ignored. "Now the global epidemic situation is still very grim, and the vaccination rate of China vaccine is still not high, which is far from universal immunization, so we still need to attach great importance to it and guard against the risk of importing the epidemic."
At present, the global epidemic situation in COVID-19 has not ended, and some countries have even lost control of the epidemic situation. We are always exposed to the risk of the epidemic situation and are always affected by imported cases. Therefore, timely vaccination is the safest, most efficient and most economical way to realize group immunity.
Five Domestic COVID-19 Vaccines
Approved conditional listing or emergency use
Beijing Bio-COVID-19 Vaccine, a national medicine, stands out from the encirclement and is the first to be certified by the World Organization. It is also the only inactivated vaccine among the six approved vaccines.
At the beginning of the epidemic, China laid out five technical routes for vaccine research and development: inactivated vaccine, adenovirus vector vaccine, gene recombination vaccines, attenuated influenza virus vector vaccine and nucleic acid vaccine. At present, three Covid-19 vaccines produced by five manufacturers have been approved for conditional marketing or emergency use.
Three kinds of inactivated vaccines
It was produced by Sinopharm Group China Bio-Beijing Institute of Biological Products Co., Ltd. (Beijing Institute), Wuhan Institute of Biological Products Co., Ltd. (Wuhan Institute) and Beijing Kexing Zhongwei Biotechnology Co., Ltd. (Kexing Zhongwei) respectively. The main principle is to use African green monkey kidney (Vero) cells to culture and amplify the virus, inactivate the virus by β-propiolactone, retain antigen components to induce immune response, and add aluminum hydroxide adjuvant to improve immunogenicity. The vaccine needs 2 doses, and the interval between the two doses is recommended to be ≥3 weeks, and the second dose should be completed as soon as possible within 8 weeks.
An adenovirus vector vaccine
Produced by Kangxinuo Bio-Co., Ltd., the principle is to recombine the spike glycoprotein (S protein) gene of the new coronavirus into the replication-deficient human adenovirus type 5 gene, and the recombinant adenovirus expresses Covid-19 S protein antigen in vivo to induce immune response, and the vaccine only needs one dose.
A recombinant subunit vaccine
Produced by Anhui Zhifeilong Kema Biopharmaceutical Co., Ltd., the principle is to recombine the new coronavirus S protein receptor binding region (RBD) gene into China hamster ovary (CHO) cell gene, express it in vitro to form RBD dimer, and add aluminum hydroxide adjuvant to improve immunogenicity.
The vaccine needs 3 doses, and the interval between two adjacent doses is recommended to be ≥4 weeks. The second dose should be completed within 8 weeks after the first dose, and the third dose should be completed within 6 months after the first dose.
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Original title: "One COVID-19 vaccine hits 2 people, is it wrong? Guangdong CDC responded! 》
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